Journal of Korean Dental Association

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J Korean Dent Assoc. 1974;12(6):419-423. Published online June 30, 1974.
Cortisone 및 Calcium이 국소마취약의 Acetylcholine 근련축억제효과에 미치는 영향
배유홍1, 함종대2, 이상신3
1서울대학교 치과대학
2서울대학교 치과대학
3서울대학교 치과대학
Yu-Hong Baei1, Jhong-Dai Hahm2, Sang-Sin Lee3
Abstract
The authors have investigated the roles of cortisone and calcium on the depressive effects of local anesthetics on the acetylcholine-induced skeletal muscle contraction in frog. The results are as follows. 1. Tetracaine, cocaine, lidocaine and procaine decreased the acetylcholine-induced skeletal muscle contraction. 2. Cortisone increased the depressive effects of local anesthetics on the acetyl-choline-induced skeletal muscle contraction. 3. There was a tendency that in high calcium concentration, the depressive effects of cocaine and lidocaine on acetylcholine-induced skeletal muscle contraction were increased.

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