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ORIGINAL ARTICLE
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J Korean Dent Assoc. 2023;61(11):706-712. Published online October 31, 2023.
DOI: https://doi.org/10.22974/jkda.2023.61.11.002
- Root coverage achieved with a connective tissue graft overlaid onto allogeneic demineralized dentin matrix incorporated with rhBMP-2
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Han-wool Kwak1
, In-Woong Um2
, Jeong-Kui Ku1
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1Department of Oral and Maxillofacial Surgery, School of Dentistry and Institute of Oral Bioscience, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University
2R&D Institute, Korea Tooth Bank -
- Corresponding author: Jeong-Kui Ku Email: kujk@jbnu.ac.kr
- Received: June 14, 2023; Revised: July 4, 2023 Accepted: September 7, 2023.
- Abstract
- Autogenous demineralized dentin matrix (DDM) has been widely used in implant dentistry and highlighted as a potential carrier of recombinant human bone morphogenetic protein-2 (rhBMP-2). Allogeneic DDM (Allo-DDM) is comparable to autogenous DDM in safety and effectiveness. The various endogenous growth factors in dentin, including BMP, transform-ing growth factor, fibroblast growth factor, and insulin growth factor suggest that DDM incorporated with rhBMP-2 (DDM/ rhBMP-2) may exert a synergistic effect that promotes soft tissue healing through angiogenic activity, in addition to its osteoinductivity. This case report describes a successful outcome of root coverage where connective tissue graft (CTG) was overlaid onto Allo-DDM incorporated with rhBMP-2 (Allo-DDM/rhBMP-2).
Keywords :demineralized dentin matrix; connective tissue graft; fistula closure; dentistry; root coverage
