-
ORIGINAL ARTICLE
-
J Korean Dent Assoc. 2023;61(12):768-782. Published online November 30, 2023.
DOI: https://doi.org/10.22974/jkda.2023.61.12.002
-
최경석
, 박철영
, 김지현
, 김혜진
, 류재영
, 국민석
, 박홍주
, 오희균
, 정승곤
-
전남대학교 치의학전문대학원 구강악안면외과학 교실, 전남대학교 치의학연구소
-
- Recurrence - Related Factors of Medication Related Osteonecrosis of the Jaw (MRONJ) ; a Retrospective study
-
Kyoungseok Choi
, Chulyoung Park
, Ji Hyun Kim
, Hye Jin Kim
, Jaeyung Ryu
, Min-suk Kook
, Hong-Ju Park
, Hee-Kyun Oh
, Seunggon Jung
-
Department of Oral and Maxillofacial Surgery, School of Dentistry, Dental Science Research Institute, Chonnam National University
-
- Corresponding author: Kyoungseok Choi Tel: +82-62-530-5610, Fax: +62-530-5615, Email: dent.fletcherchoi@gmail.com
- Received: September 26, 2023; Revised: October 12, 2023 Accepted: November 7, 2023.
- Abstract
- Duration of administration of related medications, presence of bacterial infections in necrotic areas, and methods of treatment have been suggested as factors related to the recurrence of MRONJ. The purpose of this study was to investigate recurrence risk factors in patients who had undergone surgical treatment. The recurrence rate was statistically significant when the teeth affected by alveolar bone necrosis were removed together. When comparing patients who received post-operative antibiotic treatment, recurrence was significantly reduced. Comprehensive surgical approaches, including the extraction of adjacent teeth during surgery, and appropriate post-operative antibiotic therapy can be effective strategies for reducing the recurrence rate of MRONJ.
Keywords :MRONJ; Bisphosphonate; Recurrence; Drug-holiday
